Istradefylline

  ( 1 citations )    
Product Datasheet
Catalog Number:5147
Alternate Names:KW-6002
Chemical Name:8-[(1E)-2-(2-(3,4-Dimethoxyphenyl)ethenyl]-1,3-diethyl-3,7-dihydro-7-methyl-1H-purine-2,6-dione
Product Details
Citations (1)
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Biological Activity
Potent and selective adenosine A2A receptor antagonist (Ki values are 2.2 and 150 nM for A2A and A1 receptors respectively). Anticataleptic and antiparkinson agent; reverses drug-induced motor dysfunction in animal models.
Technical Data
  • M.Wt:
    384.43
  • Formula:
    C20H24N4O4
  • Solubility:
    Soluble to 20 mM in DMSO
  • Purity:
    >99
  • Storage:
    Store at +4°C
  • CAS No:
    155270-99-8
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for Istradefylline include:

1 Citations: Showing 1 - 1

  1. On the role of A2A and D2 receptors in control of cocaine and food-seeking behaviors in rats.
    Authors: Wydra Et al.
    PLoS One  2015;232:1767

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