Letrozole

  ( 2 citations )    
Product Datasheet
Catalog Number:4382
Alternate Names:CGS 20267
Chemical Name:4,4'-(1H-1,2,4-Triazol-1-ylmethylene)bisbenzonitrile
Product Details
Citations (2)
Reviews
Biological Activity
Potent, reversible non-steroidal aromatase inhibitor (IC50 = 11.5 nM). Displays antitumor effects in several animal models. Suppresses the endogenous aromatase-induced proliferation of MCF-7 cells.
Technical Data
  • M.Wt:
    285.3
  • Formula:
    C17H11N5
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
    >99
  • Storage:
    Store at +4°C
  • CAS No:
    112809-51-5
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Product Datasheets
Citations:

The citations listed below are publications that use Tocris products. Selected citations for Letrozole include:

2 Citations: Showing 1 - 2
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  1. Oestradiol synthesized by female neurons generates sex differences in neuritogenesis.
    Authors: Ruiz-Palmero Et al.
    Scientific Reports  2016;6:31891
  2. Endogenous 17β-estradiol is required for activity-dependent long-term potentiation in the striatum: interaction with the dopaminergic system.
    Authors: Tozzi Et al.
    Front Cell Neurosci  2015;9:192

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