Leuprolide

Name: Leuprolide
Brand: Tocris Bioscience
SKU: 2873

Tocris Bioscience | Catalog # 2873

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Product Documents

GnRH receptor agonist

Discontinued Product

2873 has been discontinued. View all GnRH Agonist products.

Technical Data
Reviews

Product Description
Product Specifications
Solubility
Calculators
Background References
Product Documents
Specific Notices

Key Product Details

Description

GnRH receptor agonist

Alternative Names

Leuoprorelin

View all GnRH Agonist »

Product Description

Leuprolide is a gonadotropin-releasing hormone (GnRH, luteinizing hormone-releasing hormone, LHRH) receptor agonist. Suppresses estradiol, LH and FSH serum levels and represses the growth of experimental rat endometriosis.

Product Specifications for Leuprolide

Molecular Weight

1209.41

Formula

C₅₉H₈₄N₁₆O₁₂

Storage

Desiccate at -20°C

CAS Number

53714-56-0

PubChem ID

90488782

InChI Key

GFIJNRVAKGFPGQ-UILVTTEASA-N

SMILES

[H]N1[C@@H](CCC1=O)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)NCC

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Soluble to 0.5mg/ml in water

Calculators

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Mass

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Background References

References are publications that support the biological activity of the product.

Uday LHRH antagonist attenuates the effect of fluox. on marble-burying behavior in mice. Eur.J.Pharmacol. 2007 PMID: 17368614
Salvador Effects of the luteinising hormone-releasing hormone (LH-RH) agonist leupr. on adenylyl cyclase regulation through G-protein coupled receptors in rat ventral prostate. Eur.J.Pharmacol.
Okada One-month release injectable microcapsules of a luteinizing hormone-releasing hormone agonist (leuprolide acetate) for treating experimental endometriosis in rats. J.Pharmacol.Exp.Ther. 1988 PMID: 3126294

Product Documents for Leuprolide

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for Leuprolide

For research use only

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