Loreclezole hydrochloride

  ( 2 citations )    
Product Datasheet
Catalog Number:1295
Chemical Name:(Z)-1-[2-Chloro-2-(2,4-dichlorophenyl)ethenyl]-1H-1,2,4-triazole hydrochloride
Product Details
Citations (2)
Reviews
Biological Activity
Subtype-selective GABAA receptor modulator. Acts as a positive allosteric modulator of β2 or β3-subunit containing receptors. Also acts as a negative modulator at a novel regulatory site, enhancing GABAA receptor sensitization. Inhibits homomeric ρ1 GABAC receptors.
Technical Data
  • M.Wt:
    311
  • Formula:
    C10H6Cl3N3.HCl
  • Solubility:
    Soluble to 5 mM in DMSO with gentle warming and to 5 mM in ethanol with gentle warming
  • Purity:
    >99
  • Storage:
    Desiccate at -20°C
  • CAS No:
    117857-45-1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Product Datasheets
COA view current batch
or select another batch:
Citations:

The citations listed below are publications that use Tocris products. Selected citations for Loreclezole hydrochloride include:

2 Citations: Showing 1 - 2
Filter your results:

  1. Stress-hyperresponsive WKY rats demonstrate depressed dorsal raphe neuronal excitability and dysregulated CRF-mediated responses.
    Authors: Lemos Et al.
    Neuropsychopharmacology  2011;36:721
  2. Hearing loss prevents the maturation of GABAergic transmission in the auditory cortex.
    Authors: Kotak Et al.
    Mol Med  2008;18:2098

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Have you used Loreclezole hydrochloride?

Submit a review and receive a $25US/€18/£15/$25CAN amazon gift card if you include an image - $10US/€7/£6/$10CAN Amazon card for reviews without an image. Limited to verified customers in USA, Canada and Europe.

Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.

Order Details

Contact Us to Order
reload

Feedback

Customer Information
Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

R&D Systems Guarantee