LY 215840

  ( 4 citations )    
Product Datasheet
Catalog Number:1523
Chemical Name:[8β(1S,2R)]-N-(2-Hydroxycyclopentyl)-6-methyl-1-(1-methylethyl)-ergoline-8-carboxamide
Product Details
Citations (4)
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Reviews
Biological Activity
5-HT 25-HT 7 receptor antagonist. Reduces stimulatory effect of serotonin on aldosterone secretion; also reduces 5-HT-induced cAMP formation (pK B = 8.26).
Technical Data
  • M.Wt:
    395.54
  • Formula:
    C24H33N3O2
  • Solubility:
    Soluble to 100 mM in DMSO and to 25 mM in ethanol
  • Purity:
    >98
  • Storage:
    Store at +4°C
  • CAS No:
    137328-52-0
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Product Datasheets
Citations:

The citations listed below are publications that use Tocris products. Selected citations for LY 215840 include:

4 Citations: Showing 1 - 4
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  1. A Miniaturized Screen of a Schistosoma mansoni Serotonergic G Protein-Coupled Receptor Identifies Novel Classes of Parasite-Selective Inhibitors.
    Authors: Chan Et al.
    PLoS Pathog  2016;12:e1005651
  2. Ergot Alkaloids (Re)generate New Leads as Antiparasitics.
    Authors: Chan Et al.
    BMC Neurosci  2015;9:e0004063
  3. 5-HT is a potent relaxant in rat superior mesenteric veins.
    Authors: Watts Et al.
    PLoS Negl Trop Dis  2015;3:e00103
  4. Adrenergic and serotonin receptors affect retinal superoxide generation in diabetic mice: relationship to capillary degeneration and permeability.
    Authors: Du Et al.
    FASEB J  2015;29:2194

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VersaClone cDNA Plasmids
Description Application Cat# Citations Images  

Human 5-HT7 (NP_000863) VersaClone cDNA

RDC0251
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Human 5-HT7 (NP_062874) VersaClone cDNA

RDC0252
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