MeBIO

  ( 1 citations )    
Product Datasheet
Catalog Number:3873
Chemical Name:(2'Z,3'E)-6-Bromo-1-methylindirubin-3'-oxime
Product Details
Citations (1)
Supplemental Products
Reviews
Biological Activity
Control analog of 6-bromoindirubin-3'-oxime (BIO). Displays minimal activity against CDK1/Cyclin B, GSK-3 α/β, and CDK5/p25 (IC50 values are 92.0, 44-100 and >100 μM respectively). Aryl hydrocarbon receptor (AhR) agonist; causes redistribution of AhR to the nucleus.

Active Analog also available.

Technical Data
  • M.Wt:
    370.2
  • Formula:
    C17H12BrN3O2
  • Solubility:
    Soluble to 10 mM in DMSO
  • Purity:
    >99
  • Storage:
    Store at +4°C
  • CAS No:
    667463-95-8
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Other Product-Specific Information:
Product Datasheets
Citations:

The citations listed below are publications that use Tocris products. Selected citations for MeBIO include:

1 Citations: Showing 1 - 1

  1. TIAM1 Antagonizes TAZ/YAP Both in the Destruction Complex in the Cytoplasm and in the Nucleus to Inhibit Invasion of Intestinal Epithelial Cells.
    Authors: Diamantopoulou Et al.
    Cancer Cell  2017;31:621

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