MLH1 Antibody (164C819)

Novus Biologicals | Catalog # NB100-56552

Novus Biologicals

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Canine (93%), Mouse (93%). Backed by our 100% Guarantee.

Applications

Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # 164C819
View all MLH-1 Primary Antibodies »

Product Specifications

Immunogen

This antibody was generated by immunizing mice with a synthetic peptide corresponding to amino acids 387-403 DSREQKLDAFLQPLSKP of human MLH1; GenBank no. NP_000240.1.

Reactivity Notes

93% sequence identity with mouse and canine proteins.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Scientific Data Images for MLH1 Antibody (164C819)

Western Blot: MLH1 Antibody (164C819) [NB100-56552]

Western Blot: MLH1 Antibody (164C819) [NB100-56552]

Western Blot: MLH1 Antibody (164C819) [NB100-56552] - Analysis of MLH1 in Daudi cell lysate using this antibody at 2 ug/ml.

Applications for MLH1 Antibody (164C819)

Application
Recommended Usage

Western Blot

2-3 ug/ml
Application Notes
In Molt-4, a 83 kDa band is observed.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS containing 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: MLH-1

Human Mul L Homologue (MLH1) is homologous to the bacterial DNA mismatch repair Mult L gene. Mutations in the hMLH1 gene is associated with hereditary non-polyposis colon cancer and various other cancers.

Long Name

mutL Homolog 1

Alternate Names

MLH1

Entrez Gene IDs

4292 (Human); 17350 (Mouse)

Gene Symbol

MLH1

UniProt

P40692 (Human)

Additional MLH-1 Products

Product Documents for MLH1 Antibody (164C819)

Certificate of Analysis

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Product Specific Notices for MLH1 Antibody (164C819)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

Cancer Biomarkers

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