C5L2, also known as GPR77, is a 45 kDa 7TM receptor that binds the complement proteins C3a, C4a, and C5a as well as the acylation stimulating peptide (ASP). C5L2 is expressed on various hematopoietic cells where it promotes complement-mediated inflammation. ASP binding to C5L2 on adipocytes triggers triglyceride synthesis and glucose uptake and inhibits lipolysis.
Mouse C5L2/GPR77 (Q8BW93) VersaClone cDNA
R&D Systems | Catalog # RDC0107
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Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: C5L2/GPR77
Long Name
C5a Anaphylatoxin Chemotactic Receptor C5L2
Alternate Names
GPR77
Gene Symbol
C5AR2
UniProt
Additional C5L2/GPR77 Products
Product Documents for Mouse C5L2/GPR77 (Q8BW93) VersaClone cDNA
Certificate of Analysis
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Product Specific Notices for Mouse C5L2/GPR77 (Q8BW93) VersaClone cDNA
For research use only
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