MRE 3008F20

Catalog # Availability Size / Price Qty
4041/10
MRE 3008F20 | CAS No. 252979-43-4 | Adenosine A3 Receptor Antagonists
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Description: Highly potent and selective adenosine A3 receptor antagonist

Chemical Name: N-[2-(2-Furanyl)-8-propyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl]-N'-(4-methoxyphenyl)urea

Purity: ≥98%

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Biological Activity

Potent adenosine A3 receptor competitive antagonist. Selective for human A3 receptors over human A1 and A2A receptors (Ki values are 0.29, 141 and 1197 nM respectively). Potently inhibits agonist-induced cyclic AMP elevation in resting T lymphocytes (IC50 = 5 nM).

Technical Data

M.Wt:
432.44
Formula:
C21H20N8O3
Solubility:
Soluble to 50 mM in DMSO
Purity:
≥98%
Storage:
Store at RT
CAS No:
252979-43-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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