MXRA8/DICAM Antibody - BSA Free

Novus Biologicals | Catalog # NBP2-83239

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Format

BSA Free
View all MXRA8/DICAM Primary Antibodies »

Product Specifications

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human MXRA8/DICAM. Peptide sequence: ADEGTYSCHLHHHYCGLHERRVFHLTVAEPHAEPPPRGSPGNGSSHSGAP The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Scientific Data Images for MXRA8/DICAM Antibody - BSA Free

Western Blot: MXRA8/DICAM Antibody [NBP2-83239]

Western Blot: MXRA8/DICAM Antibody [NBP2-83239]

Western Blot: MXRA8/DICAM Antibody [NBP2-83239] - Host: Rabbit. Target Name: MXRA8. Sample Tissue: Human MCF7 Whole Cell lysates. Antibody Dilution: 1ug/ml

Applications for MXRA8/DICAM Antibody - BSA Free

Application
Recommended Usage

Western Blot

1.0 ug/ml

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Format

BSA Free

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: MXRA8/DICAM

DICAM, also known as Limitrin and MXRA8, is a transmembrane adhesion protein that is expressed on the endothelium of many tissues. In the vascular system, it is found on pericytes, vascular endothelial cells (EC), and the vessel-contacting feet of astrocytes. It is upregulated on EC by VEGF and functions as a negative regulator of angiogenesis. It inhibits VEGF-induced signaling, cell migration, capillary tube formation, and in vivo angiogenesis, and promotes EC apoptosis. The interaction of DICAM with Integrin alpha V beta 3 enhances cell adhesion and inhibits the differentiation of osteoclasts.

Long Name

Matrix-Remodelling Associated 8

Alternate Names

Asp3, DICAM, Limitrin

Gene Symbol

MXRA8

Additional MXRA8/DICAM Products

Product Documents for MXRA8/DICAM Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for MXRA8/DICAM Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

Immunoglobulin Superfamily CAMs

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