DICAM, also known as Limitrin and MXRA8, is a transmembrane adhesion protein that is expressed on the endothelium of many tissues. In the vascular system, it is found on pericytes, vascular endothelial cells (EC), and the vessel-contacting feet of astrocytes. It is upregulated on EC by VEGF and functions as a negative regulator of angiogenesis. It inhibits VEGF-induced signaling, cell migration, capillary tube formation, and in vivo angiogenesis, and promotes EC apoptosis. The interaction of DICAM with Integrin alpha V beta 3 enhances cell adhesion and inhibits the differentiation of osteoclasts.
MXRA8/DICAM Antibody - BSA Free
Novus Biologicals | Catalog # NBP2-83239
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Western Blot: MXRA8/DICAM Antibody [NBP2-83239]
Western Blot: MXRA8/DICAM Antibody [NBP2-83239] - Host: Rabbit. Target Name: MXRA8. Sample Tissue: Human MCF7 Whole Cell lysates. Antibody Dilution: 1ug/mlApplications for MXRA8/DICAM Antibody - BSA Free
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Product Specific Notices for MXRA8/DICAM Antibody - BSA Free
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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