Catalog # Availability Size / Price Qty
N-Nonyldeoxynojirimycin | CAS No. 81117-35-3 | Glycosylase Inhibitors
1 Image
Description: Glucosidase inhibitor
Alternative Names: NN-DNJ

Chemical Name: (2R,3R,4R,5S)-2-(Hydroxymethyl)-1-nonyl-3,4,5-piperidinetriol

Product Details

Biological Activity

N-Nonyldeoxynojirimycin is a glucosidase inhibitor (IC50 values are 0.42 and 8.4 μM for acid α-glucosidase and α-1,6-glucosidase respectively). Inhibits liver glycogen breakdown in vivo. Also acts as a chemical chaperone; chaperones β-Glu folding at neutral p.H. allowing the stabilized enzyme to transit from the endoplasmic reticulum to the golgi, enabling proper trafficking to the lysosome.

Technical Data

Soluble to 100 mM in DMSO and to 100 mM in ethanol
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Inhibition of glycogen breakdown by imino sugars in vitro and in vivo.
    Andersson et al.
    Biochem.Pharmacol., 2004;67:697
  2. Cellular effects of deoxyojirimycin analogues: inhibition of N-linked oligosaccharide processing and generation of free glucosylated oligosaccharides.
    Mellor et al.
    Biochem.J., 2004;381:867
  3. Chemical chaperones increase the cellular activity of N307S β-glucosidase: a therapeutic strategy for Gaucher disease.
    Sawkar et al.
    Proc.Natl.Acad.Sci.USA, 2002;99:15428

Product Datasheets

Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Molarity Calculator


*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).


No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for N-Nonyldeoxynojirimycin

There are currently no reviews for this product. Be the first to review N-Nonyldeoxynojirimycin and earn rewards!

Have you used N-Nonyldeoxynojirimycin?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.