Potent, endogenous neuromedin U receptor agonist (EC50
values are 65 and 91 pM at NMU1
respectively). Induces phase shifts in the circadian rhythm of locomotor activity following i.c.v. administration. Potent endogenous anorexigenic peptide.
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Identification of neuromedin S and its possible role in the mammalian circadian oscillator system.
Mori et al.
EMBO J., 2005;24:325
Neuromedin S is a novel anorexigenic hormone.
Ida et al.
Emerging pharmacology and physiology of neuromedin U and the structurally related peptide neuromedin S.
Mitchell et al.