NS 1738

  ( 2 citations )    
Product Datasheet
Catalog Number:2995
Chemical Name:N-(5-Chloro-2-hydroxyphenyl)-N'-[2-chloro-5-(trifluoromethyl)phenyl]urea
Product Details
Citations (2)
Supplemental Products
Reviews
Biological Activity
Selective positive allosteric modulator of α7 nicotinic acetylcholine receptors. Exhibits no substantial activity for α4β2, α3β3 and α1-containing receptors. Displays cognitive-enhancing properties in vivo.
Technical Data
  • M.Wt:
    365.13
  • Formula:
    C14H9Cl2F3N2O2
  • Solubility:
    Soluble to 100 mM in DMSO and to 100 mM in ethanol
  • Purity:
    >99
  • Storage:
    Store at RT
  • CAS No:
    501684-93-1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Product Datasheets
Citations:

The citations listed below are publications that use Tocris products. Selected citations for NS 1738 include:

2 Citations: Showing 1 - 2
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  1. The influence of allosteric modulators and transmembrane mutations on desensitisation and activation of α7 nicotinic acetylcholine receptors.
    Authors: Chatzidaki Et al.
    Int J Oncol  2015;97:75
  2. Pharmacological Characterisation of Nicotinic Acetylcholine Receptors Expressed in Human iPSC-Derived Neurons.
    Authors: Chatzidaki Et al.
    Neuropharmacology  2015;10:e0125116

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