Oleanolic acid

Catalog # Availability Size / Price Qty
6026/50
Cat.No. 6026 - Oleanolic acid | C30H48O3 | CAS No. 508-02-1
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Description: Selective GPBA receptor (TGR5) partial agonist

Chemical Name: (3β)-3-Hydroxyolean-12-en-28-oic acid

Purity: ≥97%

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Biological Activity

GPBA receptor (TGR5) partial agonist (EC50 = 2.25 μM; 72% efficacy). Displays no activity at FXR. Also inhibits protein phosphate 1B (PTP1B) and glycogen phosphorylase. Suppresses cell proliferation and increases apoptosis in T24 bladder cancer cells. Antidiabetic, antihyperglycaemic, antitumor and hepatoprotective.

Technical Data

M.Wt:
456.7
Formula:
C30H48O3
Solubility:
Soluble to 20 mM in DMSO with gentle warming
Purity:
≥97%
Storage:
Store at +4°C
CAS No:
508-02-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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