Chemical Name: 6-(Benzylamino)-2-(2-hydroxyethylamino)-9-methylpurine
Biological ActivityATP-competitive cyclin-dependent kinase (cdk) inhibitor (reported IC50 values are 0.6 and 0.94 - 8 μM for cdk7 and cdk2 respectively, and >1 μM for cdk1 and cdk9. Induces cell cycle arrest at G1 in human fibroblasts.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Cellular effects of olomoucine, an inhibitor of cyclin-dependent kinases.
Abraham et al.
The cyclin-dependent kinase inhibitors olomoucine and roscovitine arrest human fibroblasts in G1 phase by specific inhibition of CDK2 kinase activity.
Alessi et al.
Inhibition of cyclin-dependent kinases by purine analogues.
Vesely et al.
How selective are pharmacological inhibitors of cell-cycle-regulating cyclin-dependent kinases?
Jorda et al.
Citation for Olomoucine
The citations listed below are publications that use Tocris products. Selected citations for Olomoucine include:
1 Citation: Showing 1 - 1
Association of luteinizing hormone receptor gene expression with cell cycle progression in granulosa cells.
Authors: Cannon Et al.
Am J Physiol Endocrinol Metab 2009;296:E1392
No product specific FAQs exist for this product, however you mayView all Small Molecule FAQs
Reviews for Olomoucine
There are currently no reviews for this product. Be the first to review Olomoucine and earn rewards!
Have you used Olomoucine?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image