Cyclin-dependent Kinase Inhibitors: Products

"Cyclin-dependent Kinase Inhibitors" has 46 results in Products.
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(R)-CR8 

Cdk inhibitor; potently inhibits cdk1 and cdk2; also inhibits CK1; acts as molecular glue

PD 0332991 isethionate 

Potent cdk4 and cdk6 inhibitor; brain penetrant

Kenpaullone 

GSK-3β inhibitor; also inhibits cdks

Senexin A 

Cdk8 inhibitor

Roscovitine 

Cdk inhibitor

THAL SNS 032 

Potent and selective Cdk9 Degrader (PROTAC®)

Ribociclib 

Dual cdk4/cdk6 inhibitor; orally bioavailable

Purvalanol A 

Cdk inhibitor; potently inhibits cdk1, cdk2 and cdk5

Purvalanol B 

Selective cdk inhibitor; potently inhibits cdk1, cdk2 and cdk5

Indirubin-3'-oxime 

GSK-3β inhibitor; also inhibits cdks and other protein kinases

NSC 663284 

Potent, selective Cdc25 phosphatase inhibitor

[Ala92]-p16 (84-103) 

Cdk 4 inhibitor peptide; derived from p16

Aminopurvalanol A 

Selective cdk inhibitor; potently inhibits cdk1, cdk2 and cdk5

NSC 625987 

Cdk4 inhibitor

Arcyriaflavin A 

Potent cdk4 inhibitor; also potently inhibits CaM kinase II; antiviral

Ryuvidine 

SETD8 inhibitor; also CDK4 inhibitor

SU 9516 

Cdk inhibitor; potently inhibits cdk1 and cdk2

Flavopiridol hydrochloride 

Cdk inhibitor; potently inhibits cdk2 and cdk9

NU 2058 

Cdk1 and cdk2 inhibitor

PHA 767491 hydrochloride 

Cdk inhibitor; potently inhibits cdk9; also inhibits MK2

NU 6140 

Cdk2 inhibitor; also potent inhibitor of aurora kinase A and B

(R)-DRF053 dihydrochloride 

Potent CK1 inhibitor; also inhibits cyclin-dependent kinases

AZD 5438 

Cdk inhibitor; potently inhibits cdk1, 2, 5 and 9

SNS 032 

Cdk inhibitor; potently inhibits cdk2, cdk7 and cdk9

Ro 3306 

Cdk1 inhibitor

CGP 60474 

Potent cdk inhibitor

CGP 74514 dihydrochloride 

Potent CDK1 inhibitor

BS 181 dihydrochloride 

Selective cdk7 inhibitor

R 547 

Potent and selective cdk inhibitor; orally bioavailable

BMS 265246 

Cdk inhibitor; potently inhibits cdk1 and cdk2

CVT 313 

Cdk2 and cdk5 inhibitor

Alsterpaullone 

Potent CDK1 and CDK2 inhibitor; also inhibits GSK-3β and Lck

BRD 6989 

Cdk8 inhibitor; enhances IL-10 production

NVP 2 

Potent and selective ATP-competitive CDK9 inhibitor

LDC 000067 

Potent and selective CDK9 inhibitor

K 03861 

Potent CDK2 inhibitor

BSJ-03-123 

Selective Cdk6 Degrader (PROTAC®)

BSJ-04-132 

Selective Cdk4 Degrader (PROTAC®)

BSJ-03-204 

Selective Cdk4/6 Degrader (PROTAC®)

YKL 5-124 

Potent and selective CDK7 inhibitor; induces cell cycle arrest

FMF-04-159-2 

Potent covalent CDK14 and CDK16 inhibitor; also inhibits other TAIRE kinase family members

FMF-04-159-R 

Potent CDK14 and CDK16 inhibitor; displays reversible inhibition of CDK14

SMIP 004 

SKP2 (S-phase kinase-associated protein 2) inhibitor; upregulates p27 and arrests cell cycle in G1 phase

Dabrafenib mesylate 

Potent and selective B-Raf, CDK16 and NEK9 inhibitor; anticancer; also targets human proteins in the SARS-CoV-2 interactome

Dinaciclib 

Potent and selective inhibitor of CDK2, CDK5, CDK1 and CDK9

CDK8/19i 

Potent and selective CDK8 and CDK19 inhibitor; maintains pluripotency of mouse PSCs in culture
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