ω-Conotoxin MVIIC
Tocris Bioscience | Catalog # 1084
CaV2.x blocker
Discontinued Product
1084 has been discontinued.
View all Cav2.x Channel Blockers products.
Product Description
ω-Conotoxin MVIIC is a peptide neurotoxin; wide spectrum blocker of N, P and Q type calcium channels.Licensing Information
Sold under license from the University of Utah.
Product Specifications for ω-Conotoxin MVIIC
Molecular Weight
2749.00
Formula
C106H178N40O32S7
Storage
Desiccate at -20°C
CAS Number
147794-23-8
PubChem ID
90479752
InChI Key
FHVUTHWUIUXZBY-IXEXBNPISA-N
SMILES
[H]N[C@H]1CSSC[C@@H]2NC(=O)[C@@H]3CSSC[C@H](NC(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@H](CSSC[C@H](NC(=O)[C@@H]4CCCN4C(=O)[C@H](C)NC(=O)CNC(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@H](CCCCN)NC1=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)NC([C@@H](C)O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CC(O)=O)C(=O)N3)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CO)NC2=O)C(N)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
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Solubility
| Solubility | Soluble to 1mg/ml in water |
Calculators
Background References
References are publications that support the biological activity of the product. See our Citations tab to view 24 publications citing the usage of this product.
- McDonough Inhibition of Ca2+ channels in rat central and peripheral neurons by ω-conotoxin MVIIC. J.Neurosci. 1996 PMID: 8786437
- Hillyard A new conus peptide ligand for mammalian presynaptic Ca2+ channels. Neuron 1992 PMID: 1352986
Product Documents for ω-Conotoxin MVIIC
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for ω-Conotoxin MVIIC
For research use only
Related Research Areas
Citations for ω-Conotoxin MVIIC
Customer Reviews for ω-Conotoxin MVIIC (2)
4.5 out of 5
2 Customer Ratings
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Species: MouseAssay Type: Ex VivoCell Line/Tissue: CerebellumVerified Customer | Posted 06/21/2023omega -Conotoxin MVIIC in combination with tetrodotoxin was used to clear stimulation artifact from whole-cell electrophysiological response of cerebellar granule cell. Top trace: control response; bottom trace: conotoxin (10 nM) + omega -Conotoxin MVIIC (1 microM) added to perfusion solution.
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Species: HumanAssay Type: In VitroCell Line/Tissue: MCF-7Verified Customer | Posted 03/15/2020We used all these compounds which were dissolved in DMSO and added to fresh culture media. Concentration reference paper PMID: 27186076
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