Peptide YY (3-36)

Catalog # Availability Size / Price Qty
Peptide YY (3-36)
1 Image
Description: Selective NPY Y2 receptor agonist
Alternative Names: PYY 3-36

Purity: ≥95%

Product Details
Citations (1)
Supplemental Products

Biological Activity

Peptide YY (3-36) is a Y2 selective agonist. IC50 values are 0.11 and 1050 nM for inhibition of 125I-PYY binding to Y2 and Y1 receptors respectively. Inhibits food intake and reduces weight gain in vivo. Brain penetrant.

Technical Data


(Modifications: Tyr-34 = C-terminal amide)

Soluble to 1 mg/ml in water
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Gut hormone PYY3-36 physiologically inhibits food intake.
    Batterham et al.
    Nature, 2002;418:650
  2. Primary structures of PYY, [Pro34]PYY and PYY-(3-36) confer different conformations and receptor selectivity.
    Keire et al.
    Am.J.Physiol.Gastrointest.Liver Physiol., 2000;279:G126
  3. Characterization of blood-brain barrier permeability to PYY3-36 in the mouse.
    Nonaka et al.
    J.Pharmacol.Exp.Ther., 2003;306:948

Product Datasheets

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Citation for Peptide YY (3-36)

The citations listed below are publications that use Tocris products. Selected citations for Peptide YY (3-36) include:

1 Citation: Showing 1 - 1


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