Biological Activity Y2 selective agonist. IC50 values are 0.11 and 1050 nM for inhibition of 125I-PYY binding to Y2 and Y1 receptors respectively. Inhibits food intake and reduces weight gain in vivo. Brain penetrant.
(Modifications: Tyr-34 = C-terminal amide)
Soluble to 1 mg/ml in water
Desiccate at -20°C
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