Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

DyLight 550 (Excitation = 562 nm, Emission = 576 nm)

Antibody Source

Monoclonal Mouse IgG2A Clone # 537237
View all Plexin B2 Primary Antibodies »

Product Specifications

Immunogen

Chinese hamster ovary cell line CHO-derived recombinant human Plexin B2
Leu20-Arg1160
Accession # O15031

Specificity

Detects human Plexin B2 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human Plexin A4, B1, B3, C1, D1, or recombinant mouse Plexin A1, A2, or A3 is observed.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Applications for Plexin B2 Antibody (537237) [DyLight 550]

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Plexin B2

Plexin B2, also known by its gene name PLXNB2, has 1,838 amino acids and is approximately 205kDa. Plexin B2 is a member of the Plexin family, and localizes to the cell membrane as a transmembrane receptor. Plexin B2 is a receptor for Semaphorins, such as SEMA4C, SEMA4D and SEMA4G, and is implicated in cell migration, cell-cell signaling, and axon guidance. Current research on Plexin B2 is being performed in relation to several diseases and disorders including leukemia, neuronitis and Situs inversus. Plexin B2 has also been shown to have interactions with MET, PFDN1, HMOX2, MST1R, and MLF1IP in the axon guidance pathway.

Alternate Names

MM1, PLEXB2, PLXNB2

Gene Symbol

PLXNB2

Additional Plexin B2 Products

Product Documents for Plexin B2 Antibody (537237) [DyLight 550]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for Plexin B2 Antibody (537237) [DyLight 550]



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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