[Pro3]-GIP (Mouse)

   
Product Datasheet
Catalog Number:5838
Chemical Name:
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Biological Activity
GIP receptor antagonist (IC50 = 2.6μM). Inhibits GIP-stimulated insulin release from pancreatic β cells in vitro. In ob/ob mice, blocks the effects of GIP on insulin release and plasma glucose levels. Also improves intraperitoneal glucose tolerance, insulin sensitivity, and glucose response to feeding in ob/ob mice.
Technical Data
  • M.Wt:
    4971.62
  • Formula:
    C225H342N62O64S
  • Sequence:
    YAPGTFISDYSIAMDKIRQQDFVNWLLAQRGKKSDWKHNITQ
  • Solubility:
    Soluble to 2 mg/ml in water
  • Storage:
    Store at -20°C
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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