PSB 36

  ( 4 citations )    
Product Datasheet
Catalog Number:2019
Chemical Name:1-Butyl-8-(hexahydro-2,5-methanopentalen-3a(1H)-yl)-3,7-dihydro-3-(3-hydroxypropyl)-1H-purine-2,6-dione
Product Details
Citations (4)
Supplemental Products
Reviews
Biological Activity
Potent and selective A1 adenosine receptor antagonist. Displays binding affinities of 0.12, 187, 552, 6500 and 2300 nM for rA1, hA2B, rA2A, rA3 and hA3 receptors respectively. Demonstrates greater selectivity than DPCPX (Cat. No. 0439).
Technical Data
  • M.Wt:
    386.49
  • Formula:
    C21H30N4O3
  • Solubility:
    Soluble to 100 mM in DMSO and to 100 mM in ethanol
  • Purity:
    >99
  • Storage:
    Desiccate at +4°C
  • CAS No:
    524944-72-7
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Product Datasheets
Citations:

The citations listed below are publications that use Tocris products. Selected citations for PSB 36 include:

4 Citations: Showing 1 - 4
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  1. Overexpression of BDNF increases excitability of the lumbar spinal network and leads to robust early locomotor recovery in completely spinalized rats.
    Authors: Ziemlinska Et al.
    PLoS One  2014;9:e88833
  2. Influence of age, body temperature, GABAA receptor inhibition and caffeine on the Hering-Breuer inflation reflex in unanesthetized rat pups.
    Authors: Arnal Et al.
    Respir Physiol Neurobiol  2013;186:73
  3. Adenosine A(2) receptors modulate tubuloglomerular feedback.
    Authors: Carlström Et al.
    Am J Physiol Renal Physiol  2010;299:F412
  4. Paraxanthine, the primary metabolite of caffeine, provides protection against dopaminergic cell death via stimulation of ryanodine receptor channels.
    Authors: Guerreiro Et al.
    Mol Pharmacol  2008;74:980

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