Potent and selective A1
adenosine receptor antagonist, both in vitro
and in vivo
values are 3.9, 130, 50 and 4000 nM for human A1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Metabolic challenge to glia activates and adenosine-mediated safety mechanism that promotes neuronal survival by delaying the onset of spreading depression waves.
Canals et al.
J.Cereb.Blood Flow Metab., 2008;28:1835
Adenosine receptors and their ligands.
Naunyn Schmiedebergs Arch.Pharmacol., 2000;362:382
An experimental paradigm for investigating the role of endogenous adenosine/A1 receptor interactions in vivo.
Kuan et al.
Effects of 1,3-dipropyl-8-cyclopentylxanthine (DPCPX), a highly selective adenosine receptor antagonist, on force of contraction in guinea-pig atrial and ventricular cardiac preparations.
Von der Leyen
Naunyn Schmiedebergs Arch.Pharmacol., 1989;340:204
The citations listed below are publications that use Tocris products. Selected citations for DPCPX include:
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