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PU 23

6885 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
6885/50
6885/10
PU 23 | CAS No. 817635-93-1 | Multidrug Transporter Inhibitors
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Description: Multidrug resistance protein (MRP) 4 inhibitor

Chemical Name: N-[[[4-[[(Phenylmethyl)amino]sulfonyl]phenyl]amino]thioxomethyl]benzamide

Purity: ≥98%

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Biological Activity

PU 23 is a multidrug resistance protein (MRP) 4 inhibitor. Sensitizes MRP4-overexpressing cells to the anticancer agent 6-Mercaptopurine (Cat. No. 4103; 6-MP) (IC50 values are 14.11 and 6.06 μM in the absence and presence of compound, respectively). Increases accumulation of 6-MP in MRP4-overexpressing cells.

Technical Data

M.Wt:
425.52
Formula:
C21H19N3O3S2
Solubility:
Soluble to 50 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
817635-93-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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