6-Mercaptopurine

Catalog # Availability Size / Price Qty
4103/50
6-Mercaptopurine | CAS No. 50-44-2 | DNA, RNA and Protein Synthesis Inhibitors
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Description: Purine analog; inhibits DNA and RNA synthesis

Chemical Name: Purine-6(1H)-thione

Purity: ≥99%

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Biological Activity

Inhibitor of de novo purine synthesis through interference with DNA and RNA synthesis. Immunosuppressive and antileukemic drug; reduces the anticoagulation elicited by warfarin. Active metabolite of azathioprine (Cat. No. 4099).

Technical Data

M.Wt:
152.18
Formula:
C5H4N4S
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in 1eq. NaOH
Purity:
≥99%
Storage:
Store at RT
CAS No:
50-44-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Clinical pharmacology and pharmacogenetics of thiopurines.
    Sahasranaman et al.
    Eur.J.Clin.Pharmacol., 2008;64:753

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