Mesothelin, also known as CAK1 and ERC, is derived from a precursor that also includes Megakaryocyte Potentiating Factor (MPF). Following cleavage of the precursor, Mesothelin remains attached to the cell surface via a GPI linkage. Mesothelin is normally expressed on mesothelial cells in the pleura, pericardium, and peritoneum as well as in the developing and postnatal pancreas. It is upregulated in mesotheliomas and a range of carcinomas and adenomas. Mesothelin promotes tumor cell proliferation, migration, anchorage-independent growth, and tumor progression.
Quantikine Immunoassay Control Set 717 for Human Mesothelin
R&D Systems | Catalog # QC225
For use with catalog number DMSLN0
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Key Product Details
Species
Human
Applications
Control
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Formulation, Preparation, and Storage
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Background: Mesothelin
Alternate Names
CAK1, MPF, MSLN, SMR
Gene Symbol
MSLN
Additional Mesothelin Products
Product Documents for Quantikine Immunoassay Control Set 717 for Human Mesothelin
Certificate of Analysis
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Note: Certificate of Analysis not available for kit components.
Product Specific Notices for Quantikine Immunoassay Control Set 717 for Human Mesothelin
For research use only
Related Research Areas
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