(R)-Baclofen
Tocris Bioscience | Catalog # 0796
Key Product Details
Description
Alternative Names
Product Description
More active enantiomer of (RS)-Baclofen, a selective GABAB agonist.
Racemate also available.
Product Specifications for (R)-Baclofen
Molecular Weight
Formula
Storage
Purity
Chemical Name
CAS Number
PubChem ID
InChI Key
SMILES
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 4.27 | 20 with gentle warming |
Preparing Stock Solutions for (R)-Baclofen
The following data is based on the product molecular weight 213.66.
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.2 mM | 23.40 mL | 117.01 mL | 234.02 mL |
| 1 mM | 4.68 mL | 23.40 mL | 46.80 mL |
| 2 mM | 2.34 mL | 11.70 mL | 23.40 mL |
| 10 mM | 0.47 mL | 2.34 mL | 4.68 mL |
Calculators
Background References
References are publications that support the biological activity of the product. See our Citations tab to view 85 publications citing the usage of this product.
- Hong Effects of phaclofen and the enantiomers of bac. on cardiovascular responses to intrathecal administration of L- and D-baclofen in the rat. Eur.J.Pharmacol. 1991 PMID: 1654254
- Falch Comparative stereostructure-activity studies on GABAA and GABAB receptor sites and GABA uptake using rat brain membrane preparations. J.Neurochem. 1986 PMID: 3016189
Product Documents for (R)-Baclofen
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for (R)-Baclofen
For research use only
Related Research Areas
Citations for (R)-Baclofen
Customer Reviews for (R)-Baclofen (1)
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Species: MouseAssay Type: Ex VivoVerified Customer | Posted 10/22/2018Used to activate GABAb, direct application. Although it did not trigger any response, neither did GABA and this was expected, used it to confirm GABAb is not involved in our assay.
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