Rad1 Antibody (4126) - Azide and BSA Free

Novus Biologicals | Catalog # NB100-346

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Validated:

Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2A Clone # 4126

Format

Azide and BSA Free
View all Rad1 Primary Antibodies »

Product Specifications

Immunogen

Amino terminal fragment of human Rad1 purified from E. coli.

Localization

Nuclear

Specificity

This is specific for Rad 1.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Theoretical MW

28 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Rad1 Antibody (4126) - Azide and BSA Free

Rad1 Antibody (4126)

Western Blot: Rad1 Antibody (4126) [NB100-346] -

Western Blot: Rad1 Antibody (4126) [NB100-346] - Whole cell extract (30 ug) was separated by 12% SDS-PAGE, and the membrane was blotted with Rad1 antibody [4126] (NB100-346) diluted at 1:1000. The HRP-conjugated anti-mouse IgG antibody was used to detect the primary antibody, and the signal was developed with Trident ECL plus-Enhanced.

Applications for Rad1 Antibody (4126) - Azide and BSA Free

Application
Recommended Usage

Western Blot

1:1000

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS, 20% Glycerol

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Rad1

Human Rad1 is a component of a heterotrimeric PCNA-like complex that also contains the Rad9 and Hus1 proteins. This complex is believed to be involved in cellular responses to DNA damage, possibly by associating with Rad17 and several components of the PCNA-loading heteropentamer, replication factor C. Human Rad1 exhibits significant homology to Rad1 from S. pombe, and its expression in yeast rad1 mutants has been shown to partially restore radiation resistance and G2-checkpoint activity. It has also been shown to possess exonuclease activity.

Alternate Names

cell cycle checkpoint protein Hrad1, checkpoint control protein HRAD1, DNA repair exonuclease rad1 homolog, DNA repair exonuclease REC1, EC 3.1.11.2, exonuclease homolog RAD1, HRAD1, RAD1 (S. pombe) homolog, RAD1 homolog (S. pombe), Rad1-like DNA damage checkpoint protein, REC1cell cycle checkpoint protein RAD1

Entrez Gene IDs

5810 (Human)

Gene Symbol

RAD1

Additional Rad1 Products

Product Documents for Rad1 Antibody (4126) - Azide and BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

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Product Specific Notices for Rad1 Antibody (4126) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for Rad1 Antibody (4126) - Azide and BSA Free

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