Ranitidine hydrochloride

Catalog # Availability Size / Price Qty
1967/50
Ranitidine hydrochloride | CAS No. 66357-59-3 | Histamine H2 Receptor Antagonists
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Description: Selective H2 antagonist

Chemical Name: N-[2-[[[5-[(Dimethylamino)methyl]-2-furanyl]methyl]thio]ethyl]-N'-methyl-2-nitro-1,1-ethanediamine hydrochloride

Purity: ≥99%

Product Details
Citations (1)
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Reviews

Biological Activity

Potent, selective and competitive histamine H2 receptor antagonist (pA2 = 6.95 - 7.2). Inhibits gastric acid secretion induced by histamine, pentagastrin, bethanecol and food in vivo. Also inhibits aspirin-induced gastric lesions.

Technical Data

M.Wt:
350.86
Formula:
C13H22N4O3S.HCl
Solubility:
Soluble to 50 mM in water
Purity:
≥99%
Storage:
Desiccate at +4°C
CAS No:
66357-59-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Some in vitro and in vivo actions of the new histamine H2-receptor antagonist, ranitidine.
    Daly et al.
    Br.J.Pharmacol., 1981;72:49
  2. Antagonism of vasodepressor and gastric secretory responses to histamine by the H2-receptor antagonists, ranitidine and cimetidine, in the anaesthetized dog.
    Daly et al.
    Br.J.Pharmacol., 1981;72:55
  3. A review of the animal pharmacology of ranitidine - a new, selective histamine H2-antagonist.
    Brittain and Daly
    Scand.J.Gastroenterol.Suppl., 1981;69:1

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Citation for Ranitidine hydrochloride

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