Chemical Name: N-[2-[[[5-[(Dimethylamino)methyl]-2-furanyl]methyl]thio]ethyl]-N'-methyl-2-nitro-1,1-ethanediamine hydrochloride
Biological ActivityRanitidine hydrochloride is a potent, selective and competitive histamine H2 receptor antagonist (pA2 = 6.95 - 7.2). Inhibits gastric acid secretion induced by histamine, pentagastrin, bethanecol and food in vivo. Also inhibits aspirin-induced gastric lesions.
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Tocris products are intended for laboratory research use only, unless stated otherwise.
Some in vitro and in vivo actions of the new histamine H2-receptor antagonist, ranitidine.
Daly et al.
Antagonism of vasodepressor and gastric secretory responses to histamine by the H2-receptor antagonists, ranitidine and cimetidine, in the anaesthetized dog.
Daly et al.
A review of the animal pharmacology of ranitidine - a new, selective histamine H2-antagonist.
Brittain and Daly
Citation for Ranitidine hydrochloride
The citations listed below are publications that use Tocris products. Selected citations for Ranitidine hydrochloride include:
1 Citation: Showing 1 - 1
Coordination of distinct but interacting rhythmic motor programs by a modulatory projection neuron using different co-transmitters in different ganglia.
Authors: Kwiatkowski Et al.
J Exp Biol 2013;216:1827
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