Catalog # Availability Size / Price Qty
Risperidone | CAS No. 106266-06-2 | 5-HT2A Receptor Antagonists
1 Image
Description: 5-HT2A antagonist; also D2 antagonist; atypical antipsychotic
Alternative Names: R 64 766

Chemical Name: 3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one

Purity: ≥99%

Product Details
Citations (2)
Supplemental Products

Biological Activity

Risperidone is an atypical antipsychotic agent that displays 5-HT2A receptor antagonism. Also displays high affinity at D2 receptors (Ki values are 0.4 and 3.13 nM for 5-HT2A and D2 receptors respectively).

Technical Data

Soluble to 10 mM in DMSO and to 10 mM in ethanol
Store at +4°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Complete Your Experiment

Additional Information

Other Product-Specific Information:

Background References

  1. Risperidone: a novel antipsychotic with balanced serotonin-DA antagonism, receptor occupancy profile, and pharmacologic activity.
    Leysen et al.
    J.Clin.Psychiatry, 1994;55:5
  2. Biochemical profile of risperidone, a new antipsychotic.
    Leysen et al.
    J.Pharmacol.Exp.Ther., 1988;247:661
  3. Risperidone: a novel antipsychotic with many "atypical" properties.
    Stathis et al.
    Psychopharmacol., 1996;127:181
  4. Structure of the D2 DA receptor bound to the atypical antipsychotic drug risperidone
    Wang et al.
    Nature, 2018;555:269

Product Datasheets

Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Molarity Calculator


*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Citations for Risperidone

The citations listed below are publications that use Tocris products. Selected citations for Risperidone include:

2 Citations: Showing 1 - 2


No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

VersaClone cDNA Plasmids

Reviews for Risperidone

There are currently no reviews for this product. Be the first to review Risperidone and earn rewards!

Have you used Risperidone?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.