High affinity 5-HT2B
receptor antagonist (pKi
= 9.5). Displays 1000-fold selectivity for 5-HT2B
with good bioavailability.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
RS-127445: a selective, high affinity, orally bioavailable 5-HT2B receptor antagonist.
Bonhaus et al.
Evidence for a control of plasma serotonin levels by 5-Hydroxytryptamine2B receptors in mice.
Callebert et al.
The citations listed below are publications that use Tocris products. Selected citations for RS 127445 hydrochloride include:
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