Recombinant Human RUNX3/CBFA3 His Protein

Name: Recombinant Human RUNX3/CBFA3 His Protein
Brand: Novus Biologicals
SKU: NBP1-44462
Price: 329 USD
Availability: InStock

Novus Biologicals | Catalog # NBP1-44462

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Product Specifications
Scientific Data
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Source

E. coli

Tag

His

Applications

SDS-PAGE

View all RUNX3/CBFA3 Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 53-186 of Human RUNX3/CBFA3

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MRSMVDVLAD HAGELVRTDS PNFLCSVLPS HWRCNKTLPV AFKVVALGDV PDGTVVTVMA GNDENYSAEL RNASAVMKNQ VARFNDLRFV GRSGRGKSFT LTITVFTNPT QVATYHRAIK VTVDGPREPR RHRQK

Purity

>95%, by SDS-PAGE

Predicted Molecular Mass

17.1 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human RUNX3/CBFA3 His Protein

SDS-PAGE: Recombinant Human RUNX3/CBFA3 His Protein [NBP1-44462]

SDS-Page: Recombinant Human RUNX3/CBFA3 Protein [NBP1-44462] - 17.1 kDa (155aa) confirmed by MALDI-TOF with a purity of 95% by SDS - PAGE

Formulation, Preparation, and Storage

NBP1-44462

Formulation	20 mM Tris-HCl buffer (pH8.0), 20% glycerol, 0.1 M NaCl, 1 mM DTT
Preservative	No Preservative
Concentration	0.5 mg/ml
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: RUNX3/CBFA3

RUNX3, also known as runt-related transcription factor 3, belongs to the RUNX family that regulate the expression of genes involved in cellular differentiation and cell cycle progression. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It is a strong candidate as a gastric cancer tumor suppressor. Recombinant human RUNX3, fused to His-tag at N-terminus, protein was expressed in E.coli and purified by using conventional chromatography techniques

Long Name

Runt-related Transcription Factor 3

Alternate Names

AML2, CBFA3, PEBP2A3, PEBP2AC

Gene Symbol

RUNX3

Additional RUNX3/CBFA3 Products

Product Documents for Recombinant Human RUNX3/CBFA3 His Protein

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Certificate of Analysis

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Product Specific Notices for Recombinant Human RUNX3/CBFA3 His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.