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S 32212 hydrochloride

4508 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
4508/10
4508/50
Cat.No. 4508 - S 32212 hydrochloride | C25H28N4O2.HCl | CAS No. 847871-78-7
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Description: 5-HT2C inverse agonist; α2 antagonist

Chemical Name: 1,2-Dihydro-N-[4-methoxy-3-(4-methyl-1-piperazinyl)phenyl]-3H-benz[e]indole-3-carboxamide hydrochloride

Purity: ≥99%

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Biological Activity

Inverse agonist of 5-HT2C receptors (pKi = 8.18 at human 5-HT2C INI receptors). Also an antagonist of human α2-adrenoceptors. Displays negligible affinity for α1A-adrenoceptors, histamine H1 receptors and muscarinic M1 receptors.

Technical Data

M.Wt:
452.98
Formula:
C25H28N4O2.HCl
Solubility:
Soluble to 25 mM in water and to 25 mM in DMSO
Purity:
≥99%
Storage:
Desiccate at RT
CAS No:
847871-78-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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VersaClone cDNA Plasmids

Human 5-HT2C (NP_000859) VersaClone cDNA

RDC0290

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