SCS

Key Product Details

Product Description

SCS is a potent and selective partial inhibitor of β1-containing GABA_A receptors (IC₅₀ values are 4.5, 5.3 and 7.9 nM at α2β1γ1θ, α2β1γ1 and α2β1γ2s GABA_A receptors respectively). May bind allosterically to a novel site on GABA_A receptor.

Product Specifications for SCS

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for SCS

The following data is based on the product molecular weight 256.26.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.5 mM	7.80 mL	39.02 mL	78.05 mL
2.5 mM	1.56 mL	7.80 mL	15.61 mL
5 mM	0.78 mL	3.90 mL	7.80 mL
25 mM	0.16 mL	0.78 mL	1.56 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 37 publications citing the usage of this product.

• Thompson Salicylidene salicylhydrazide, a selective inhibitor of β1-containing GABA_A receptors. Br.J.Pharmacol. 2004 PMID: 15100159

Product Documents for SCS