STF 31

  ( 2 citations )    
Product Datasheet
Catalog Number:4484
Chemical Name:4-[[[[4-(1,1-Dimethylethyl)phenyl]sulfonyl]amino]methyl]-N-3-pyridinylbenzamide
Product Details
Citations (2)
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Reviews
Biological Activity
Inhibitor of GLUT1; inhibits glucose uptake in renal cell carcinoma (RCC) 4 cells. Activity causes necrotic cell death in von Hippel-Lindau (VHL)-deficient RCC cells. Also NAMPT inhibitor. Eliminates human pluripotent stem cells from culture with limited toxicity towards differentiated cells.
Technical Data
  • M.Wt:
    423.53
  • Formula:
    C23H25N3O3S
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
    >99
  • Storage:
    Store at RT
  • CAS No:
    724741-75-7
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for STF 31 include:

2 Citations: Showing 1 - 2
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  1. A comparative analysis of inhibitors of the glycolysis pathway in breast and ovarian cancer cell line models.
    Authors: Xintaropoulou Et al.
    Oncotarget  2015;6:25677
  2. Inhibition of an NAD+ salvage pathway provides efficient and selective toxicity to human pluripotent stem cells.
    Authors: Kropp Et al.
    Mol Cell Biol  2015;4:483

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