STF 31

Catalog # Availability Size / Price Qty
4484/10
4484/50
STF 31 | CAS No. 724741-75-7 | Glucose Transporter Inhibitors
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Description: NAMPT inhibitor; also GLUT1 inhibitor

Chemical Name: 4-[[[[4-(1,1-Dimethylethyl)phenyl]sulfonyl]amino]methyl]-N-3-pyridinylbenzamide

Purity: ≥99%

Product Details
Citations (5)
Supplemental Products
Reviews (1)

Biological Activity

Inhibitor of GLUT1; inhibits glucose uptake in renal cell carcinoma (RCC) 4 cells. Activity causes necrotic cell death in von Hippel-Lindau (VHL)-deficient RCC cells. Also NAMPT inhibitor. Eliminates human pluripotent stem cells from culture with limited toxicity towards differentiated cells.

Technical Data

M.Wt:
423.53
Formula:
C23H25N3O3S
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥99%
Storage:
Store at RT
CAS No:
724741-75-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citations for STF 31

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We got a good result
By Anonymous on 05/07/2020
Application: Species: Human

After 72hr treatment with three different inhibitors (GPP78,STF118804, and STF31), we used 10nM to 10uM.

PMID: 31439867 Reference

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