STF 31

Tocris Bioscience | Catalog # 4484

NAMPT inhibitor; also GLUT1 inhibitor
Tocris Bioscience

Key Product Details

Description

NAMPT inhibitor; also GLUT1 inhibitor
View all Glucose Transporter Inhibitors »

Product Description

STF 31 is an inhibitor of GLUT1; inhibits glucose uptake in renal cell carcinoma (RCC) 4 cells. Activity causes necrotic cell death in von Hippel-Lindau (VHL)-deficient RCC cells. Also NAMPT inhibitor. Eliminates human pluripotent stem cells from culture with limited toxicity towards differentiated cells.

Product Specifications for STF 31

Molecular Weight

423.53

Formula

C23H25N3O3S

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

4-[[[[4-(1,1-Dimethylethyl)phenyl]sulfonyl]amino]methyl]-N-3-pyridinylbenzamide

CAS Number

724741-75-7

PubChem ID

984333

InChI Key

NGQPRVWTFNBUHA-UHFFFAOYSA-N

SMILES

O=C(NC2=CN=CC=C2)C1=CC=C(CNS(C3=CC=C(C(C)(C)C)C=C3)(=O)=O)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 42.35 100

Preparing Stock Solutions for STF 31

The following data is based on the product molecular weight 423.53.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.36 mL 11.81 mL 23.61 mL
5 mM 0.47 mL 2.36 mL 4.72 mL
10 mM 0.24 mL 1.18 mL 2.36 mL
50 mM 0.05 mL 0.24 mL 0.47 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 14 publications citing the usage of this product.

Product Documents for STF 31

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for STF 31

For research use only

Related Research Areas

Metabolism

Customer Reviews for STF 31 (1)

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  • We got a good result
    Name: Anonymous
    Species: Human
    Assay Type: In Vitro
    Cell Line/Tissue: human astrocytes
    Verified Customer | Posted 05/07/2020
    After 72hr treatment with three different inhibitors (GPP78,STF118804, and STF31), we used 10nM to 10uM.
    STF 31 4484

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