The levels of amino acids, carbohydrates and lipids in the body are dependent on the metabolic balance of catabolism and anabolism. R&D Systems offers a range of quality products to study the enzymatic cascades that govern these metabolic reactions. Adipocytokines are bioactive products produced by adipose tissue and include inflammatory mediators (IL-6, IL-8), angiogenic proteins (VEGF), and metabolic regulators (adiponectin, leptin). The levels of circulating glucose are controlled by contrasting actions of two pancreatic enzymes, insulin and glucagon. In addition, lipid metabolism is determined by the relative amounts of lipid generation, transport, storage and breakdown. Disruption of these homeostatic states results in metabolic disorders such as diabetes and obesity, and increases the risk of developing other pathological conditions (i.e. cardiovascular disease).