Chemical Name: 2-[4-(1,1-Dimethylethyl)phenoxy]cyclohexanol
Biological ActivitytBPC is a positive allosteric modulator of neuropeptide Y receptor 4 (Y4R). Potentiates Y4R response to pancreatic polypeptide (PP), neuropeptide Y (NPY) and peptide YY (PYY) (EC50 values are 0.03, 0.4 and 0.5 nM respectively). Shows selectivity for Y4R over Y1R, Y2R and Y5R.
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Tocris products are intended for laboratory research use only, unless stated otherwise.
Identification and characterization of the first selective Y4 receptor positive allosteric modulator.
Schubert et al.
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VersaClone cDNA Plasmids
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