tBPC
Chemical Name: 2-[4-(1,1-Dimethylethyl)phenoxy]cyclohexanol
Purity: ≥98%
Biological Activity
tBPC is a positive allosteric modulator of neuropeptide Y receptor 4 (Y4R). Potentiates Y4R response to pancreatic polypeptide (PP), neuropeptide Y (NPY) and peptide YY (PYY) (EC50 values are 0.03, 0.4 and 0.5 nM respectively). Shows selectivity for Y4R over Y1R, Y2R and Y5R.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Identification and characterization of the first selective Y4 receptor positive allosteric modulator.
Schubert et al.
J.Med.Chem., 2017;60:7605
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