Tenidap

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Tenidap | CAS No. 120210-48-2 | Cyclooxygenase Inhibitors
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Description: NSAID, cyclooxygenase (COX-1) inhibitor. Also opener of KIR2.3
Alternative Names: CP 66248

Chemical Name: (Z)-5-Chloro-2,3-dihydro-3-(hydroxy-2-thienylmethylene)-2-oxo-1H-indole-1-carboxamide

Purity: ≥99%

Product Details
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Biological Activity

NSAID that preferentially inhibits COX-1 (IC50 values are < 0.03, 1.2 and > 30 μM for COX-1, COX-2 and 5-lipoxygenase respectively). Inhibits formation of pro-inflammatory arachidonic acid metabolites in isolated human peripheral polymorphonuclear leukocytes. Opener of inward rectifying hKir2.3 channel (EC50 = 402 nM).

Technical Data

M.Wt:
320.75
Formula:
C14H9N2O3SCl
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥99%
Storage:
Store at +4°C
CAS No:
120210-48-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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