Potent and selective noradrenalin re-uptake inhibitor (Ki
values are 5, 77 and 1451 nM for inhibition of radioligand binding to human NET, SERT and DAT respectively). Displays minimal affinity for a range of other neurotransmitter receptors and transporters (Ki
> 1 μ
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All Tocris products are intended for laboratory research use only.
Other Product-Specific Information:
A new inhibitor of norepinephrine uptake devoid of affinity for receptors in rat brain.
Wong et al.
Atomoxetine increases extracellular levels of norepinephrine and dopamine in prefrontal cortex of rat: a potential mechanism for efficacy in attention deficit/hyperactivity disorder.
Bymaster et al.
The citations listed below are publications that use Tocris products. Selected citations for Tomoxetine hydrochloride include:
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