Human SLC6A2/NET (NP_001034) VersaClone cDNA

Name: Human SLC6A2/NET (NP_001034) VersaClone cDNA
Brand: R&D Systems
SKU: RDC1112
Price: 675 USD
Availability: InStock

R&D Systems | Catalog # RDC1112

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Background
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Specific Notices

Key Product Details

Species

Human

Accession Number

NP_001034

Background: SLC6A2/NET

Norepinephrine Transporter [NET] (or noradrenaline transporter (NAT)) is a monoamine transporter that transports the neurotransmitter noradrenaline from the synapse back to its vesicles for storage until later use. It also appears to transport the neurotransmitter dopamine in the same way, but to a lesser degree. Studies have shown a decrease in NET levels in the locus coeruleus in patients diagnosed with major depression (Klimek et al., 1997). Cocaine, amphetamines and many therapeutic antidepressants, such as the SNRIs (Serotonin-norepinephrine reuptake inhibitors) and the tricyclic antidepressants (TCAs) act to raise noradrenaline. Furthermore, deficits in the NET gene have been associated with ADHD (Kim et al., 2006).

Long Name

Norepinephrine Transporter

Alternate Names

NAT1, Noradrenalin Transporter, Norepinephrine Transporter

Entrez Gene IDs

6530 (Human); 20538 (Mouse); 83511 (Rat)

Gene Symbol

SLC6A2

UniProt

NP_001034

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Product Specific Notices for Human SLC6A2/NET (NP_001034) VersaClone cDNA

For research use only

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