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TTNPB | CAS No. 71441-28-6 | Retinoic Acid Receptor Agonists
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Description: Retinoic acid analog; RAR agonist
Alternative Names: Ro 13-7410

Chemical Name: 4-[(E)-2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl]benzoic acid

Purity: ≥98%

Product Details
Citations (7)

Biological Activity

TTNPB is an extremely potent analog of retinoic acid, selective for the retinoic acid receptor (RAR) subtype. Enhances reprogramming efficiency in chemically induced pluripotent stem cells (CiPSCs).

Technical Data

Soluble to 10 mM in DMSO
Desiccate at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Retinoid X receptor-selective ligands produce malformations in Xenopus embryos.
    Minucci et al.
    Proc.Natl.Acad.Sci.U.S.A., 1996;93:1803
  2. Arotinoids, a new class of highly active retinoids.
    Loeliger et al.
    Eur.J.Med.Chem.-Chim.Ther., 1980;15:9
  3. Pluripotent stem cells induced from mouse somatic cells by small-molecule compounds.
    Hou et al.
    Science, 2013;341:651

Product Datasheets

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Citations for TTNPB

The citations listed below are publications that use Tocris products. Selected citations for TTNPB include:

7 Citations: Showing 1 - 7


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