UK 59811 hydrochloride
Chemical Name: 3-Ethyl 5-methyl 4-(2-bromophenyl)-2-((2-(dimethylamino)ethoxy)methyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride
Biological ActivityBlocks CaVAb, a site-directed mutant of bacterial NaVAb with full voltage-dependent Ca2+ channel function (IC50 = 194 nM).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Structural basis for inhibition of a voltage-gated Ca2+ channel by Ca2+ antagonist drugs.
Tang et al.
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