UK 59811 hydrochloride

Tocris Bioscience | Catalog # 6179

CaVAb blocker
Tocris Bioscience
Discontinued Product
6179 has been discontinued. View all Non-selective Cav Blockers products.

Key Product Details

Description

CaVAb blocker
View all Non-selective Cav Blockers »

Product Description

UK 59811 hydrochloride is a blocks CaVAb, a site-directed mutant of bacterial NaVAb with full voltage-dependent Ca2+ channel function (IC50 = 194 nM).

Licensing Information

Sold for research purposes under agreement from Pfizer Inc.

Product Specifications for UK 59811 hydrochloride

Molecular Weight

517.84

Formula

C22H29BrN2O5.HCl

Storage

Store at +4°C

Purity

≥98% (HPLC)

Chemical Name

3-Ethyl 5-methyl 4-(2-bromophenyl)-2-((2-(dimethylamino)ethoxy)methyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride

CAS Number

2250025-89-7

PubChem ID

134812832

InChI Key

JZOQTVYILXBAMQ-UHFFFAOYSA-N

SMILES

CCOC(C1=C(NC(C)=C(C(OC)=O)C1C2=CC=CC=C2Br)COCCN(C)C)=O.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 10.36 20
DMSO 51.78 100

Preparing Stock Solutions for UK 59811 hydrochloride

The following data is based on the product molecular weight 517.84.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.93 mL 9.66 mL 19.31 mL
5 mM 0.39 mL 1.93 mL 3.86 mL
10 mM 0.19 mL 0.97 mL 1.93 mL
50 mM 0.04 mL 0.19 mL 0.39 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for UK 59811 hydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for UK 59811 hydrochloride

For research use only

Related Research Areas

Ion Channels and Regulators

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