Home / Non-selective Cav Blockers / UK 59811 hydrochloride

UK 59811 hydrochloride

Catalog #: 6179 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
6179/25
6179/5
UK 59811 hydrochloride | Non-selective Cav Blockers
1 Image
Description: CaVAb blocker

Chemical Name: 3-Ethyl 5-methyl 4-(2-bromophenyl)-2-((2-(dimethylamino)ethoxy)methyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride

Purity: ≥98%

Product Details
Reviews
Biological Activity Technical Data Additional Information Background Product Datasheets Calculators

Biological Activity

UK 59811 hydrochloride is a blocks CaVAb, a site-directed mutant of bacterial NaVAb with full voltage-dependent Ca2+ channel function (IC50 = 194 nM).

Technical Data

M.Wt:
517.84
Formula:
C22H29BrN2O5.HCl
Solubility:
Soluble to 20 mM in water and to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at +4°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Complete Your Research

Potent competitive NMDA antagonist
Cat # 1241
Potent DGAT-1 inhibitor
Cat # 3587
Selective P2Y6 antagonist
Cat # 2146
Selective h5-HT1B antagonist
Cat # 1242
FTO (mRNA N6-methyladenine demethylase) inhibitor; also inhibits ALKBH2 and ALKBH3
Cat # 6867
Selective Hsp90 inhibitor
Cat # 4608
NAMPT inhibitor; depletes leukemia stem cells
Cat # 5207
Positive allosteric modulator of M4 receptors
Cat # 3383
Selective PAR4 antagonist
Cat # 5387
Selective positive allosteric modulator of M4 receptors
Cat # 3141
Cdk inhibitor; potently inhibits cdk1 and cdk2
Cat # 5654
Potent, selective JAK3 inhibitor
Cat # 1366
Reversible MAO-A inhibitor
Cat # 4395
High affinity NK1 antagonist
Cat # 2400
Potent PTEN inhibitor
Cat # 3591
Dual irreversible inhibitor of ErbB2 and EGFR
Cat # 3580
MAP4K4 (HGK) inhibitor; also inhibits MINK and TNIK
Cat # 5752
Positive allosteric modulator of M5 receptors
Cat # 4404

Additional Information

Licensing Caveats:
Sold for research purposes under agreement from Pfizer Inc.

Product Datasheets

Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for UK 59811 hydrochloride

There are currently no reviews for this product. Be the first to review UK 59811 hydrochloride and earn rewards!

Have you used UK 59811 hydrochloride?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.