Vinpocetine

Name: Vinpocetine
Brand: Tocris Bioscience
SKU: 0757

Tocris Bioscience | Catalog # 0757

Submit a review

Citations (1)

Product Documents

Na+ channel blocker

Discontinued Product

0757 has been discontinued. View all Voltage-gated Sodium Channel Blockers products.

Product Description
Product Specifications
Solubility
Preparing Stock Solutions
Calculators
Background References
Product Documents
Specific Notices
Research Areas

Key Product Details

Description

Na+ channel blocker

View all Voltage-gated Sodium Channel Blockers »

Product Description

Vinpocetine is a phosphodiesterase inhibitor, selective for PDE1 (IC₅₀ = 21 μM). Also blocks voltage-gated Na⁺ channels.

Product Specifications for Vinpocetine

Molecular Weight

350.46

Formula

C₂₂H₂₆N₂O₂

Storage

Store at RT

Purity

≥99% (HPLC)

Chemical Name

(3α,16α)-Eburnamenine-14-carboxylic acid ethyl ester

CAS Number

42971-09-5

PubChem ID

443955

InChI Key

DDNCQMVWWZOMLN-IRLDBZIGSA-N

SMILES

O=C(OCC)C5=C[C@@]2(CC)[C@@]1([H])C4=C(C3=CC=CC=C3N45)CCN1CCC2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
	DMSO	3.5	10 with gentle warming
	Ethanol	17.52	50

Preparing Stock Solutions for Vinpocetine

The following data is based on the product molecular weight 350.46.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.5 mM	5.71 mL	28.53 mL	57.07 mL
2.5 mM	1.14 mL	5.71 mL	11.41 mL
5 mM	0.57 mL	2.85 mL	5.71 mL
25 mM	0.11 mL	0.57 mL	1.14 mL

Calculators

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

Volume

M. Wt*

g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Calculate the dilution required to prepare a stock solution.

Concentration 1 (C1)

Volume 1 (V1)

Concentration 2 (C2)

Volume 2 (V2)

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

Background References

References are publications that support the biological activity of the product.

Molnar and Erdo Vinpocetine is as potent as phen. to block voltage-gated Na⁺ channels in rat cortical neurons. Eur.J.Pharmacol. 1995 PMID: 7737339
Hagiwara Effect of vinpocetine on cyclic nucleotide metabolism in vascular smooth muscle. Biochem.Pharmacol. 1984 PMID: 6322804

Product Documents for Vinpocetine

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for Vinpocetine

For research use only

Related Research Areas

Ion Channels and Regulators

Citations for Vinpocetine

Customer Reviews for Vinpocetine

There are currently no reviews for this product. Be the first to review Vinpocetine and earn rewards!

Have you used Vinpocetine?

Submit a review and receive an Amazon gift card!

$25/€18/£15/$25CAN/¥2500 Yen for a review with an image

$10/€7/£6/$10CAN/¥1110 Yen for a review without an image