Chemical Name: 4-Butoxy-N-(2,4-difluorophenyl)benzamide
Biological ActivityVU 0357121 is a positive allosteric modulator of mGlu5 receptors (EC50 = 33 nM). Binds to a site distinct from that bound by MPEP (Cat. No. 1212).
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Discovery of a novel chemical class of mGlu5 allosteric ligands with distinct modes of pharmacology.
Hammond et al.
ACS Chem.Neurosci., 2010;1:702
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VersaClone cDNA Plasmids
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