Positive allosteric modulator of mGlu5
= 33 nM). Binds to a site distinct from that bound by MPEP
(Cat. No. 1212).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Discovery of a novel chemical class of mGlu5 allosteric ligands with distinct modes of pharmacology.
Hammond et al.
ACS Chem.Neurosci., 2010;1:702