Catalog Number: 4120
Chemical Name: 4,8-Dihydroxyquinoline-2-carboxylic acid
Biological Activity
Shown to selectively activate group II mGlu receptors in transfected HEK293 cells at nanomolar concentrations. Attenuates cAMP formation in mouse cortical slices expressing mGlu2 and mGlu3 receptors.
Technical Data
  • M.Wt:
    205.17
  • Formula:
    C10H7NO4
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
    >98%
  • Storage:
    Store at RT
  • CAS No:
    59-00-7
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. The tryptophan oxidation pathway in mosquitoes with emphasis on xanthurenic acid biosynthesis.
    Han et al.
    J.Insect.Physiol., 2007;53:254
  2. Xanthurenic acid, a novel endogenous ligand for metabotropic glutamate receptors.
    Mauro et al.
    Program No. 643.1/F2. 2010 Neuroscience Meeting Pl, 2010;:2010 (Online)

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