Xanthurenic acid

Discontinued Product

4120 has been discontinued.
View all Group II mGluR Activators products.
Xanthurenic acid | CAS No. 59-00-7 | Group II mGluR Activators
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Description: Selectively activates group II mGlu receptors

Chemical Name: 4,8-Dihydroxyquinoline-2-carboxylic acid

Purity: ≥98%

Product Details

Biological Activity

Xanthurenic acid is a shown to selectively activate group II mGlu receptors in transfected HEK293 cells at nanomolar concentrations. Attenuates cAMP formation in mouse cortical slices expressing mGlu2 and mGlu3 receptors.

Technical Data

Soluble to 100 mM in DMSO
Store at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Xanthurenic acid, a novel endogenous ligand for metabotropic glutamate receptors.
    Mauro et al.
    Program No. 643.1/F2. 2010 Neuroscience Meeting Pl, 2010;:2010 (Online)
  2. The tryptophan oxidation pathway in mosquitoes with emphasis on xanthurenic acid biosynthesis.
    Han et al.
    J.Insect.Physiol., 2007;53:254

Product Datasheets

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