Zaprinast

  ( 3 citations )    
Product Datasheet
Catalog Number:0947
Chemical Name:2-(2-Propyloxyphenyl)-8-azapurin-6-one
Product Details
Citations (3)
Supplemental Products
Reviews
Biological Activity
Phosphodiesterase inhibitor, selective for PDE6, 5, 11 and 9 (IC50 values are 0.15, 0.76, 12.0 and 29.0 μM respectively). Putative GPR35 agonist.
Technical Data
  • M.Wt:
    271.28
  • Formula:
    C13H13N5O2
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
    >99
  • Storage:
    Store at RT
  • CAS No:
    37762-06-4
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for Zaprinast include:

3 Citations: Showing 1 - 3
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  1. The antiallergic mast cell stabilizers lodoxamide and bufrolin as the first high and equipotent agonists of human and rat GPR35.
    Authors: MacKenzie Et al.
    Mol Pharmacol  2014;85:91
  2. Effect of the phosphodiesterase-5 inhibitor zaprinast on ischemia-reperfusion injury in rats.
    Authors: Polcari Et al.
    Proc Natl Acad Sci U S A  2013;27:338
  3. Ob receptor in rabbit ovary and leptin in vitro regulation of corpora lutea.
    Authors: Zerani Et al.
    J Endourol  2004;183:279

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