TC-G 1001

Key Product Details

Product Description

TC-G 1001 is a GPR35 agonist (pEC₅₀ values are 7.59 and 8.36 for β-arrestin and Gα_q-i5 Ca²⁺ assays respectively). Displays 1000-fold greater potency at human GPR35 receptors relative to mouse and rat GPR35 orthologs in an IP1 accumulation assay. More potent than zaprinast (Cat. No. 0947).

Product Specifications for TC-G 1001

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for TC-G 1001

The following data is based on the product molecular weight 342.34.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	29.21 mL	146.05 mL	292.11 mL
0.5 mM	5.84 mL	29.21 mL	58.42 mL
1 mM	2.92 mL	14.61 mL	29.21 mL
5 mM	0.58 mL	2.92 mL	5.84 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Neetoo-Isseljee High-throughput identification and characterization of novel, species-selective GPR35 agonists. J.Pharmacol.Exp.Ther. 2013 PMID: 23262279

Product Documents for TC-G 1001