Prostaglandin E1/PGE1

Prostaglandin E1 (PGE1) is synthesized from dihomo-g-linolenic acid (DGLA). PGE1 has a number of biological actions including vasodilation, proliferation of vascular smooth muscle cells, platelet aggregation, and insulin-like effects. PGE1 elicits receptor-mediated elevation of cAMP. It is the major prostaglandin in semen.