Catalog Number: 1620
Alternate Names: PGE1, Prostaglandin E1
Chemical Name: (11α,13E,15S)-11,15-Dihydroxy-9-oxo-prost-13-en-1-oic acid
Biological Activity
Prostaglandin with some selectivity for EP3 and EP4 receptors (Ki values are 1.1, 2.1, 36, 10� and 33 nM for mouse EP3, EP4, EP1, EP2 and IP receptors respectively). Inhibits platelet aggregation and is a vasodilator in vivo.
Technical Data
  • M.Wt:
    354.49
  • Formula:
    C20H34O5
  • Solubility:
    Soluble to 50 mM in ethanol
  • Purity:
    >98%
  • Storage:
    Store at -20°C
  • CAS No:
    745-65-3
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Ligand binding specificities of the eight types and subtypes of the mouse prostanoid receptors expressed in Chinese hamster ovary cells.
    Kiriyama et al.
    Br.J.Pharmacol., 1997;122:217
  2. Prostaglandin E1: a review.
    Kirtland
    Prostaglandins Leukot.Essent.Fatty Acids, 1988;32:165
  3. Specificity between the anti-aggregatory actions of prostacyclin, prostaglandin E1 and D2 on platelets.
    Whittle et al.
    Adv.Exp.Med.Biol., 1985;192:109

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