Alprostadil

Key Product Details

Product Description

Alprostadil is a prostaglandin with some selectivity for EP₃ and EP₄ receptors (K_i values are 1.1, 2.1, 36, 10 and 33 nM for mouse EP₃, EP₄, EP₁, EP₂ and IP receptors respectively). Inhibits platelet aggregation and is a vasodilator in vivo.

Product Specifications for Alprostadil

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for Alprostadil

The following data is based on the product molecular weight 354.49.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

4 3 2 1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.5 mM	5.64 mL	28.21 mL	56.42 mL
2.5 mM	1.13 mL	5.64 mL	11.28 mL
5 mM	0.56 mL	2.82 mL	5.64 mL
25 mM	0.11 mL	0.56 mL	1.13 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 24 publications citing the usage of this product.

• Kirtland Prostaglandin E₁: a review. Prostaglandins Leukot.Essent.Fatty Acids 1988 PMID: 2901111
• Whittle Specificity between the anti-aggregatory actions of prostacyclin, prostaglandin E₁ and D₂ on platelets. Adv.Exp.Med.Biol. 1985 PMID: 2871707
• Kiriyama Ligand binding specificities of the eight types and subtypes of the mouse prostanoid receptors expressed in Chinese hamster ovary cells. Br.J.Pharmacol. 1997 PMID: 9313928

Product Documents for Alprostadil