2 results for "Akt" in Products

Akt Products

Akt1, Akt2, and Akt3 make up a family of serine/threonine kinases, often activated downstream of growth factor receptors and PI 3-Kinase. Each Akt family member contains an N-terminal pleckstrin homology (PH) domain, a central kinase domain, and a C-terminal regulatory domain. They have putative roles in cell proliferation and survival, and Akt perturbations are thought to play an important role in tumorigenesis.

PI 3-K/Akt/mTOR signaling inhibitor; blocks phosphorylation of Akt and p70S6K in vitro

Chemical Name: 3,8-Dihydroxy-6H-dibenzo[b,d]pyran-6-one
Purity: ≥98%
PI 3-K/Akt/mTOR signaling inhibitor; blocks phosphorylation of Akt and p70S6K in vitro
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Promotes Akt hyperphosphorylation; decreases phosphorylation of Akt substrates

Chemical Name: 6-(2-Benzothiazolyl)-1-ethyl-2-[(1E)-2-(methylphenylamino)ethenyl]-3-phenyl-1H-benzimidazolium iodide
Purity: ≥98%
Promotes Akt hyperphosphorylation; decreases phosphorylation of Akt substrates
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