114 results for "Akt" in Products
Akt Products
Akt1, Akt2, and Akt3 make up a family of serine/threonine kinases, often activated downstream of growth factor receptors and PI 3-Kinase. Each Akt family member contains an N-terminal pleckstrin homology (PH) domain, a central kinase domain, and a C-terminal regulatory domain. They have putative roles in cell proliferation and survival, and Akt perturbations are thought to play an important role in tumorigenesis.
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, Flow, Simple Western, CyTOF-ready |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2B Monoclonal Clone #281046 |
| Applications: | IHC, WB, Flow, ICC/IF, Simple Western, + 1 More |
Contains 4 sets of 2 membranes - each spotted in duplicate with antibodies against 37 different kinases and 2 related total proteins
| Reactivity: | Human |
| Reactivity: | Human, Mouse, Rat |
| Assay Range: | 156-10000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #545007 |
| Applications: | WB, Simple Western |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #HL2915 |
| Applications: | IHC, WB, ICC/IF |
Selective inhibitor of Akt/PKB signaling. Antitumor and antiviral
| Alternate Names: | Triciribine,NSC 154020,TCN |
| Chemical Name: | 1,5-Dihydro-5-methyl-1-β-D-ribofuranosyl-1,4,5,6,8-pentaazaacenaphthylen-3-amine |
| Purity: | ≥98% |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, Simple Western |
Selective Akt/PKB inhibitor
| Alternate Names: | Akt Inhibitor X |
| Chemical Name: | 10-[4'-(N,N-Diethylamino)butyl]-2-chlorophenoxazine hydrochloride |
| Purity: | ≥98% |
Akt kinase inhibitor. Antitumor
| Chemical Name: | 4-[2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[(3S)-3-piperidinylmethoxy)-1H-imidazo[4,5-c]pyridin-4-yl]-2-methyl-3-butyn-2-ol |
| Purity: | ≥98% |
PI 3-K/Akt/mTOR signaling inhibitor; blocks phosphorylation of Akt and p70S6K in vitro
| Chemical Name: | 3,8-Dihydroxy-6H-dibenzo[b,d]pyran-6-one |
| Purity: | ≥98% |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, Simple Western |
![Western Blot: AKT [p Thr450] Antibody [NBP3-13168]](https://resources.rndsystems.com/images/products/AKT-[p-Thr450]-Antibody-Western-Blot-NBP3-13168-img0004.jpg "Western Blot: AKT [p Thr450] Antibody [NBP3-13168]")
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #SR2061 |
| Applications: | IHC, WB, ICC/IF |
Akt activator
| Chemical Name: | 2-Amino-6-chloro-α-cyano-3-(ethoxycarbonyl)-4H-1-benzopyran-4-acetic acid ethyl ester |
PKB/Akt inhibitor; also modulates Kv2.1 current
| Alternate Names: | KRX-0401 |
| Chemical Name: | Octadecyl-(1,1-dimethyl-4-piperidylio) phosphate |
| Purity: | ≥98% |
Potent and selective dual Akt1 and 2 inhibitor
| Alternate Names: | Akt Inhibitor VIII |
| Chemical Name: | 1,3-Dihydro-1-[1-[[4-(6-phenyl-1H-imidazo[4,5-g]quinoxalin-7-yl)phenyl]methyl]-4-piperidinyl]-2H-benzimidazol-2-one |
| Purity: | ≥98% |
Promotes Akt hyperphosphorylation; decreases phosphorylation of Akt substrates
| Chemical Name: | 6-(2-Benzothiazolyl)-1-ethyl-2-[(1E)-2-(methylphenylamino)ethenyl]-3-phenyl-1H-benzimidazolium iodide |
| Purity: | ≥98% |
Potent pan-Akt and PKA inhibitor
| Chemical Name: | 4-(4-Chlorophenyl)-4-[4-(1H-pyrazol-4-yl)phenyl]piperidine hydrochloride |
| Purity: | ≥98% |
SPOP E3 ubiquitin ligase inhibitor
| Chemical Name: | 1,5-Dihydro-2-imino-10-methyl-N-[2-(4-methyl-1-piperazinyl)ethyl]-5-oxo-1-[2-(2-thienyl)ethyl]-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide |
| Purity: | ≥98% |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: AKT [p Ser473] Antibody [NBP3-13120]](https://resources.rndsystems.com/images/products/AKT-[p-Ser473]-Antibody-Western-Blot-NBP3-13120-img0003.jpg "Western Blot: AKT [p Ser473] Antibody [NBP3-13120]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, Flow, CyTOF-ready |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, Flow, CyTOF-ready |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, Flow, CyTOF-ready |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, Flow, CyTOF-ready |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, Flow, CyTOF-ready |